C3 (atipia probablemente benigna)

Los aspirados en esta categoría pueden tener todas las características de un aspirado benigno. Además una combinación de otras características que no se observan usualmente en los aspirados benignos. Estas pueden ser:

• Pleomorfismo nuclear
• Pérdida de la cohesividad
• Hipercromasia nuclear y cambios citológicos secundarios a (embarazo, anticonceptivos, terapia de suplencia hormonal) u otros tratamientos
• Hipercelularidad acompañando las características anteriores

Nuclear crowding and hypercellularity.

Nuclear pleomorphism.

Initial loss of cellular cohesion.

Nuclear hyperchromasia.

Some fibroadenomata may show a certain degree of cellular crowding and some nuclear enlargement…

..but the presence of myoepithelial and stromal cells lead towards a diagnosis of fibroadenoma.

..but the presence of myoepithelial and stromal cells lead towards a diagnosis of fibroadenoma.

Some papillomata show three dimensional groups of slightly enlarged ductal elements with some nuclear pleomorphism and chromatin clumping.

Some papillomata show three dimensional groups of slightly enlarged ductal elements with some nuclear pleomorphism and chromatin clumping.

Tubular carcinoma: A tubular carcinoma may mimic a fibroadenoma but observe the lack of myoepithelial cells and the mild degree of nuclear pleomorphism in tubular carcinoma.

Fibroadenoma: A tubular carcinoma may mimic a fibroadenoma but observe the lack of myoepithelial cells and the mild degree of nuclear pleomorphism in tubular carcinoma.