Non-gynaecological Cytology
Effusions cytology
| Physiopathology of the effusions |
| Specimen collection and preparation methods |
| Accuracy |
| Reporting terminology |
| Benign elements |
| Non-neoplastic conditions |
| Malignant effusions |
Primary effusion lymphoma
It is a large B-cell lymphoma which presents as a pleural, pericardial or peritoneal effusion. There is no associated mass lesion or lymphadenopaty. Most cases arise in the setting of HIV infection. The prognosis is poor.
Cytologic diagnostic features
- Dispersed large cells
- Round or irregular nuclei, prominent nucleoli
- Abundant basophilic cytoplasm (Romanowsky stain)
Immunocytochemistry confirms the diagnosis: they are usually CD45 positive, CD19 and CD20 negative.
81 82
CD3 (84) Ki-67 (85)
