C2 (benign)

This category indicates an adequate sample without evidence of significant atypia or malignancy.

Benign cases consist of monolayers of uniform ductal cells with round-oval shaped nuclei whose size is similar to that of red blood cells.

Dispersed individual and paired naked nuclei can be seeni in the background

If a cyst has been aspirated, then a mixture of foamy macrophages and regular apocrine cells may be part of the cytological picture.

Fragments of fibro-fatty tissue are also common findings.

 

 

 

 


 

 

 


 

 

 



 

 

 

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To summarise

The main cytological criteria of benign lesions are:

Monolayer of uniform ductal cells
Appropriate cellular orientation
Good intercellular cohesion
Small sized nuclei (size similar to that of red blood cells)
Myoepithelial/stromal elements/naked bipolar nuclei